AI-generated imageLongevity blood biomarkers: going beyond 'normal' lab results
Reference ranges in lab results are population statistics, not an individual target. They tell you whether you fall within the range of people who were tested — not whether you're in a state that predicts good function twenty years from now.
Program 21 defines the set of markers we measure and the target ranges we use when planning interventions.
Why 'normal' isn't the same as optimal
A value at the lower or upper edge of the reference range often means a decade of slow drift toward what will eventually be labelled a disease. The trend over years is more informative than any single measurement.
That's why we read every result along three dimensions: absolute value, position within the range, and direction of change relative to previous measurements.
Baseline set of markers
The panel is designed to cover the four systems that most determine your healthy-years range: cardiovascular, metabolic, inflammatory and hormonal.
- Extended lipids: ApoB, Lp(a), LDL subclasses — not just total cholesterol.
- Metabolic: fasting glucose, insulin, HOMA-IR, HbA1c, liver enzymes.
- Inflammation: hs-CRP, homocysteine, ferritin.
- Hormones: total and free testosterone, SHBG, estradiol, TSH, fT3, fT4, DHEA-S, morning cortisol.
- Micronutrients: vitamin D, B12, folate, magnesium, zinc.
Hormonal balance past 40
The drop in energy after forty is often blamed on age, though test results usually show it as a combination of lowered free testosterone, subclinical hypothyroidism and chronic vitamin D deficiency.
We never interpret hormone values in isolation. SHBG, insulin sensitivity and sleep quality determine how much of a measured value is even biologically available.
From result to action
Every change is introduced with a clear hypothesis and a pre-defined re-testing date. Without that, a panel becomes a collection of numbers without decisions.
We typically retest after 10–12 weeks, since most markers don't stabilise sooner. The exception is inflammatory markers, which can be checked earlier.
- One or two interventions at a time, never the whole set at once.
- Retest under identical conditions: same time of day, same pre-test routine.
- Medications and hormone replacement therapy are prescribed and managed exclusively by a physician.
Relating the program to your baseline
The professional team can help select appropriate measurements, monitor change and assess the effect in the context of your data.
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Results are individual and vary between people; they do not represent a promise of a specific outcome. HUMAX organizes and coordinates measurements and consultations carried out by independent licensed specialists, and does not perform healthcare activities.
This program is a general starting point. What makes sense for you is determined at an initial triage consultation (€150, 45 minutes) — resulting in a written proposal for your measurement scope, with no obligation.